Synthesis and biological evaluation of pyridinebetaine A and B.
نویسندگان
چکیده
The synthesis of the marine natural products pyridinebetaine A and B is reported. The biological evaluation of pyridinebetaine A and B and several analogues as cytotoxic, antifungal and antiviral agents is also described. Unfortunately, none of the compounds tested showed relevant antifungal or cytotoxic activity. Only pyridinebetaine B reduced the Herpes simplex virus type 1 virus replication, though only weakly.
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عنوان ژورنال:
- Natural product research
دوره 23 16 شماره
صفحات -
تاریخ انتشار 2009